Re: Suicide
Posted: July 26th, 2017, 2:13 pm
Did you find an alternative solution?Finrock wrote: ↑July 26th, 2017, 1:47 pmYou can look at the Side Affects listed on WebMD for a quick reference. It doesn't call it serotonin syndrome, but it describes some of the symptoms. The issue is of course compounded if you are using SSRIs (for instance) in addition to 5-HTP. However, 5-HTP gets converted in to serotonin so in large doses it is possible to have too much serotonin in the body.brlenox wrote: ↑July 26th, 2017, 11:42 amFrom my research, I have not found where 5-HTP is ever implicated in serotonin syndrome. Typically this is related to drugs which manipulate serotonin levels. In the few instances where 5-HTP is associated it has always been when used in conjunction with those types of drugs. If you have other research though I would be interested.Finrock wrote: ↑July 26th, 2017, 9:21 amJust as a word of caution concerning 5-HTP, because it affects serotonin levels in the body, it can cause serotonin syndrome if too much is taken just as SSRIs can. 5-HTP increases serotonin levels directly, whereas SSRI's suppress the reuptake of serotonin in the body to increase the amount left in the body. Both are acting on serotonin in the body, however.brlenox wrote: ↑July 26th, 2017, 9:06 am
There are actually four groups:
1.) The "S" (Serotonin) Group
2.) The "G" (GABA) Group
3.) The "D" (Dopamine) Group
4.)The "N" (Norepinephrine) Group
The one most potentially negative if misdiagnosed is the GABA. As it slows impulses then if given to a depressed person can further aggravate depression. Nonetheless, it is not considered a great risk one just needs to be on top of it to determine if it is helping or hurting. It is also the one some think is least likely to be effective as the size of the GABA molecule exceeds the blood / brain barrier tolerances. This is currently the predominate supposition as they are not sure as it does help certain patients quite well. They are wondering if it is because the Blood / Brain barrier has been "stretched" due to the issues of depression and such that it allows the molecule to pass through but again they are not sure yet if that is the case. It may simply be that something else is at play that is allowing it to work as it does prove effective far more than would be expected for a blood / brain barrier issue. Here is another link for GABA which gives a bit more detail on usage:
http://www.denvernaturopathic.com/news/GABA.html
SAMe and 5-HTP at first glance appear similar but there are a couple of different symptoms that would point to one over the other. 5 - HTP also has the affect of influencing GABA management in the body as well by magnifying it's effectiveness. Both groups have sleep issues but the issues are slightly different and that was the deciding factor for which one my wife took versus which one my child takes.
I would only start one at a time, and if it were me and I was unsure, since there is overlap in GABA performance, I would tend towards the 5-HTP first for 6 weeks or until it was obvious it was not working because issues were not responding as expected and or were getting worse. Again more research might paint a more clear picture for you but I reiterate that these have been very helpful for us.
-Finrock
Although I've never been officially diagnosed with serotonin syndrome, I have experienced what were symptoms which are typically associated with serotonin syndrome after experimenting with 5-HTP in the past. Although I was not using other SSRIs at the time, I was taking some pain medication (Tramadol) which could have contributed to the symptoms I felt, however, before I used the 5-HTP I made sure not to be using any other medications for a few days with the intent to avoid these types of issues. But, its possible that it wasn't enough time for my body to clear the "system" so to speak before I experimented with 5-HTP. I used 5-HTP for a couple of weeks and after about a week of daily use I started having issues associated with serotonin syndrome. I experimented some more trying to find the right balance but eventually gave up because for me it wasn't helping much at the time given the side effects I was experiencing.
-Finrock