Ana Maria Mihalcea, MD, PhD
Mar 8
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Autoimmune Disease
Autoimmune diseases occur when the body’s immune system starts attacking healthy tissues. It is associated with inflammation.
Vitamin D regulates immune cells, reduces inflammation, and activates immune cells that counteract autoimmune responses.
Some autoimmune disease patients have vitamin D resistance; the person becomes less responsive to vitamin D supplementation and sun exposure. Therefore, they need higher doses of vitamin D to raise their serum vitamin D levels to a suitable range.
Autoimmune specialist Dr. Cicero Coimbra, who authored the famous Coimbra Protocol, has found many of his patients with multiple sclerosis reach remission after taking massive doses of vitamin D, along with other supplements.
The protocol can start as low as 150 IU per kilogram of body weight and can potentially increase to doses as high as 1,000 IUs per kilogram of body weight daily, provided that patients are routinely tested to ensure their parathyroid hormones, calcium, and other micronutrient levels are in balance.
In an interview with The Epoch Times, Coimbra said that his clinic has treated over 15,000 patients with autoimmune diseases; among multiple sclerosis patients, around 85 percent reach remission. His protocol has also been used in rheumatoid arthritis, lupus, inflammatory bowel disease, psoriasis, and Crohn’s disease around the world, with the majority of patients following these protocols reporting significant improvements.
Regarding those who do not respond well to vitamin D treatment, Coimbra has observed that most tend to experience a high level of stress, and only by changing the way they respond to stress do they start to see improvements.
Cancer
Higher doses of vitamin D are associated with lower risks of cancer progression and mortality.
Deficiencies in B-group vitamins, vitamin C, iron, zinc, magnesium, and selenium have been linked with increased cancer risks.
Many observational studies on cancer patients have found vitamin D deficiency to also be a risk factor.
A 2016 report found that women whose vitamin D levels were raised above 40 ng/ml had a more than 65 percent lower risk of cancer incidence. Another 2019 study that followed end-term colon cancer patients found that those who increased their vitamin D levels experienced a slower worsening of their symptoms.
Grant’s research shows that vitamin D reduces the risk of cancer incidence by affecting differentiation, proliferation, and apoptosis (disintegration) of cells, prevents mortality by reducing the formation of new blood vessels to sustain tumor growth, and reduces metastasis.
Since vitamin D acts by blocking pathways that promote further cancer growth and metastasis, it is better at preventing cancer mortalities than cancer incidence, Grant said.
It is worth noting that cancer can be triggered by a multitude of factors including environmental toxins, smoking, radiation, genetics, and inflammation, many of which cannot be controlled by vitamin D intake alone.
Furthermore, it is still uncertain if vitamin D will be effective for all cancers, and the reason for cancer patients’ ailments vary from one to another.
Nonetheless, there have been case reports of cancer remission after taking high doses of vitamin D, though other factors may play into patients’ recovery.
Anesthesiologist Dr. Judson Sommerville said his patient’s wife was told by highly renowned cancer center MD Anderson Cancer Center in Houston, Texas, that she only had six months to live due to advanced ovarian cancer. She figured she had nothing to lose so she started taking high doses of vitamin D3 together with magnesium.
The patient’s wife started feeling better, and after a few months, she went to the doctor for a check-up. “They examined her and to their surprise, found her cancer-free,” Sommerville said. It has been almost 12 years and the cancer still hasn’t recurred.
Brain Health
Low vitamin D levels have been associated with higher risks of anxiety, depression, Alzheimer’s disease, Parkinson’s disease, and autism.
Vitamin D regulates chemicals in the brain that help neurons in the cortex and the hippocampus grow and survive. These two areas are involved in memory and cognitive functions, processing emotions, and complex motor functions.
Mihalcea said that the brain fog her patients experience as part of their deficiency would alleviate once she raised their vitamin D levels.
Psychiatrist Dr. John J. Cannell said in an interview with ZME Science that in treating children with autism, he has found that giving them a higher dose of 5,000 IUs a day helped nearly 80 percent of these children with their symptoms.
“My experience, having treated about 100 children with autism, is that 25 percent respond dramatically to high dose vitamin D, 50 percent respond significantly, and 25 percent do not respond at all,” he said.
How Much Vitamin D Is Necessary?
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